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Effects of LY450139 Dihydrate on Subjects With Mild to Moderate Alzheimer's Disease

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clinicaltrials.gov/study/NCT00244322
Is a
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Clinical study
0

Clinical Study attributes

NCT Number
NCT002443220
Health Conditions in Trial
Alzheimer's disease
Alzheimer's disease
0
Trial Recruitment Size
450
Trial Sponsor
Eli Lilly
Eli Lilly
0
Clinical Trial Start Date
2005
0
Study Completion Date
2006
0
Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Diagnostic0
Interventional Trial Phase
Phase 20
Official Name
LY450139: Tolerability and Biomarker Assessment in Subjects With Mild to Moderate Alzheimer's Disease0
Last Updated
May 28, 2007
0
Allocation Type
Randomized0
Intervention Model
Parallel Assignment0
Masking Type
Double0
Study summary

The purposes of this study are to determine: * The safety of LY450139 dihydrate and any side effects that might be associated with it. * How much LY450139 dihydrate should be given and how long it may be detected in blood. * To determine if LY450139 dihydrate may have an effect on a protein found in blood, called A beta. This protein is studied in subjects with Alzheimer's disease. * To collect and store samples from blood and spinal fluid for research related to Alzheimer's disease and similar (neurodegenerative) diseases or inflammation (irritation) that may provide information on how subjects respond to LY450139 or other medications. Length of study: Approximately 29 weeks. Number of office visits: 11 for most subjects: initial visit, every other week during 14 weeks of study drug treatment, and 2 follow-up visits. At no cost, approximately 45 eligible participants will receive: * Study medication * Study-related diagnostic and laboratory evaluations

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