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Leo Cancer Care

Leo Cancer Care

Leo Cancer Care is a company developing upright radiotherapy solutions.


Leo Cancer Care is a company developing upright radiotherapy devices, with both Particle Therapy and Photon Therapy fixed beams in the upright orientation.. The company's stated goal is to develop a more humane way to administer radiation therapy to patients. They aim to do this by: improving the clinical effectiveness of radiation therapy through upright positioning, reducing costs for radiation therapy by removing the need for large and expensive rotating gantries, and empowering patients to face radiation in a way that feels more personal between doctor and patient.


Leo Cancer Care (formerly Nano-X) was founded in 2014 in Sydney, Australia. It was founded based on research from the MD Anderson Cancer Centre in Houston Texas. The company is now headquartered in the United Kingdom, with a US office located in Middleton, Wisconsin. The company completed two years of product development to an ISO 13485 quality management system (QMS) before expanding to the United States to raise funds and finish the remainder of the product development.

The Ruby system developed by Leo Cancer Care

Leo Cancer Care is developing upright full radiotherapy treatment devices to treat cancer patients. The current industry practice is to position a patient horizontally on their back and to rotate a six tonne machine around them to deliver radiation from different angles to sub-millimeter accuracy. Alternatively, the Leo Cancer Care engineering team has demonstrated that by keeping the radiation fixed and instead rotating the patient, the size and cost associated with treatments can be reduced. Research from the MD Anderson Cancer Centre in Houston has shown that treatment efficacy is improved by treating patients in the upright position rather than horizontally.

The company has three products:

  • Ruby: A complete upright treatment solution—a real-time, image-guided photon radiotherapy treatment system
  • Marie: An imaging and treatment solution for upright particle therapy
  • Ada: An upright multi-axis computed tomography imaging solution


In 2016, Leo Cancer Care (known as Nano-X at the time) received $2.5M dollars in non-dilutive government grant funding after winning the New South Wales Medical Device Fund.


In 2021, Leo Cancer Care won an iF Design Awards, in collaboration with DCA Design International, for its Marie Particle Therapy Solution.


July 20, 2021
Leo Cancer Care raises $25,300,000 in series B funding. Backers included Pureland Global Venture, Yu Galaxy, WARF, Alumni Ventures, Junson Capital, Serra Ventures , CHC, Cosylab, Toret Devices and Radiation Business Solutions.
July 20, 2021
Leo Cancer Care raises a $25,300,000 series B round.
April 16, 2021
Leo Cancer Care's Marie Particle Therapy Solution wins prestigious iF Design Award, in collaboration with DCA Design International.
June 18, 2018
First Detailed Engineering Design Phase Complete

In June 2018, the first detailed design phase was closed off resulting in a full drawing pack ready for prototype manufacture.

October 2, 2017
First Formative Evaluation User Testing Completed

In October 2017, a full workflow formative evaluation was completed at the Nelune Comprehensive Cancer Centre in Sydney.

June 1, 2017
Leo Cancer Care Establishes Quality Management System

In 2017, the Quality Management System was established within which all product development has been completed.

October 3, 2016
Leo Cancer Care Wins New South Wales Medical Device Fund

In 2016, Leo Cancer Care was the recipient of a $2.5M non-dilutive government grant from New South Wales Health.

Funding rounds



Ilana Feain


Mark Strangeman

Chief Engineer

Rock Mackie


Stephen Towe


Val Theisz

Head of Regulatory Affairs

Further reading


Reassessment of the Necessity of the Proton Gantry: Analysis of Beam Orientations From 4332 Treatments at the Massachusetts General Hospital Proton Center Over the Past 10 Years

Susu Yan, Hsiao-Ming Lu, Jay Flanz, Judith Adams, Alexei Trofimov, Thomas Bortfeld


Reproducibility of patient setup in the seated treatment position: A novel treatment chair design. - PubMed - NCBI

McCarroll RE , et al.


SU-E-T-359: Patients Could (and Should) Be Treated in An Upright Position

L Court, J Yang, D Fullen, N Han, J Ko, S Mason, K Nguyen, S Stein, X Fave, M Hsieh, S Kuruvila, E Hillebrandt, J Palmer, B Beadle, B Dabaja, H Skinner, G Ibbott, P Balter


Documentaries, videos and podcasts




Ruby - radiation therapy machine

Eve - a beam-agnostic patient positioning system


July 20, 2021
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