Horizon Discovery

Gene editing refers to the process of changing regions of cellular DNA. The most common gene editing techniques involve inactivating a gene’s function (knockout), introducing or correcting a SNP mutation, or adding a reporter tag to an endogenous gene (knock-in). These changes are permanent and heritable, resulting in a newly engineered cell line.

With our Edit-R™ CRISPR-Cas9 reagents, researchers can make targeted, specific edits to any gene in practically any cell type. Additionally, Horizon offers a wide selection of pre-made edited cell lines and expert genome engineering services.

Edit-R™ gene editing reagents

Guaranteed to edit your target gene

Algorithm designed CRISPR guide RNA to maximize functional protein knockout and minimize off-target effects.

Also find numerous Cas9 nuclease options, positive and non-targeting controls, and donor templates for HDR-mediated knock-in applications.

Engineered cell models

Ready-to-go or tailored for individual needs

Find 1000's of validated knockout models, point mutations in cancer-relevant cell models, and "CRISPR-ready" stable Cas9 or dCas9-VPR expressing cell lines.

Or use our online tool to design your own cell line and get an instant quote and timeline for your next cell line engineering project.

Horizon Discovery is a developer of applications for gene editing and gene modulation for the life sciences market to support scientists in research and therapy.