Prescott Sheldon Bush (May 15, 1895 – October 8, 1972) was an American banker and politician. After working as a Wall Street executive investment banker, he represented Connecticut in the United States Senate from 1952 to 1963. A member of the Bush family, he was the father of former Vice President and President George H. W. Bush, and the paternal grandfather of former Texas Governor and President George W. Bush and former Florida Governor Jeb Bush.
Born in Columbus, Ohio, Bush graduated from Yale College and served as an artillery officer during World War I. After the war, he worked for several companies, becoming a minor partner of the A. Harriman & Co. investment bank in 1931. He served in several high-ranking United States Golf Association offices, including president of that organization. Bush settled in Connecticut in 1925.