Organization attributes
Medicinal leech therapy (hirudotherapy): a brief overview
Amrit Pal Singh 1
Affiliations expand
PMID: 20920805 DOI: 10.1016/j.ctcp.2009.11.005
Abstract
Hirudotherapy is a treatment using medicinal leeches. Hirudo medicinali, have been used to treat patients for centuries. In the past, leeches have proved to be an effective treatment for a number of conditions including battle wound treatment. Currently leeches may be used to assist in the treatment of abscesses, arthritis, glaucoma, myasthenia gravis, thrombosis and some venous disorders. Medical leeches may also be used in plastic surgery and in some blood circulatory problems. During feeding, leeches secrete a complex mixture of different biologically and pharmacologically active substances into the wound. Hirudin is the prominent constituent of leech saliva. It is sometimes used to describe all the active constituents in the leech saliva. This paper outlines the potential use of leech therapy in current medical care in India.
Copyright © 2009 Elsevier Ltd. All rights reserved.
Similar articles
A case of irritant contact dermatitis with leech.
Karadag AS, Calka O, Akdeniz N, Cecen I.
Cutan Ocul Toxicol. 2011 Sep;30(3):234-5. doi: 10.3109/15569527.2010.547543. Epub 2011 Jan 26.
PMID: 21265707
Elimination of symbiotic Aeromonas spp. from the intestinal tract of the medicinal leech, Hirudo medicinalis, using ciprofloxacin feeding.
Mumcuoglu KY, Huberman L, Cohen R, Temper V, Adler A, Galun R, Block C.
Clin Microbiol Infect. 2010 Jun;16(6):563-7. doi: 10.1111/j.1469-0691.2009.02868.x. Epub 2009 Jun 11.
PMID: 19523050
[Hirudo medicinalis-leech applications in plastic and reconstructive microsurgery--a literature review].
Knobloch K, Gohritz A, Busch K, Spies M, Vogt PM.
Handchir Mikrochir Plast Chir. 2007 Apr;39(2):103-7. doi: 10.1055/s-2007-965138.
PMID: 17497605 Review. German.
More than just one: multiplicity of Hirudins and Hirudin-like Factors in the Medicinal Leech, Hirudo medicinalis.
Müller C, Mescke K, Liebig S, Mahfoud H, Lemke S, Hildebrandt JP.
Mol Genet Genomics. 2016 Feb;291(1):227-40. doi: 10.1007/s00438-015-1100-0. Epub 2015 Aug 13.
PMID: 26267058
The return of the leech.
Abdelgabar AM, Bhowmick BK.
Int J Clin Pract. 2003 Mar;57(2):103-5.
PMID: 12661792 Review.
See all similar articles
Cited by 20 articles
Leech therapy (Hirudo medicinalis) attenuates testicular damages induced by testicular ischemia/reperfusion in an animal model.
Davoodi F, Taheri S, Raisi A, Rajabzadeh A, Zakian A, Hablolvarid MH, Ahmadvand H.
BMC Vet Res. 2021 Jul 27;17(1):256. doi: 10.1186/s12917-021-02951-5.
PMID: 34315461 Free PMC article.
Time to Change Theory; Medical Leech from a Molecular Medicine Perspective Leech Salivary Proteins Playing a Potential Role in Medicine.
Shakouri A, Wollina U.
Adv Pharm Bull. 2021 Feb;11(2):261-266. doi: 10.34172/apb.2021.038. Epub 2020 Jul 26.
PMID: 33880347 Free PMC article. Review.
Wound healing potential of bark paste of Pongamia pinnata along with hirudotherapy: A case report.
Balasooriya D, Karunarathna C, Uluwaduge I.
J Ayurveda Integr Med. 2021 Apr-Jun;12(2):384-388. doi: 10.1016/j.jaim.2021.01.014. Epub 2021 Apr 2.
PMID: 33814265 Free PMC article.
Prostaglandin E1 Is an Efficient Molecular Tool for Forest Leech Blood Sucking.
Zheng F, Zhang M, Yang X, Wu F, Wang G, Feng X, Ombati R, Zuo R, Yang C, Liu J, Lai R, Luo X, Long C.
Front Vet Sci. 2021 Jan 7;7:615915. doi: 10.3389/fvets.2020.615915. eCollection 2020.
PMID: 33490139 Free PMC article.
From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery.
Bordon KCF, Cologna CT, Fornari-Baldo EC, Pinheiro-Júnior EL, Cerni FA, Amorim FG, Anjolette FAP, Cordeiro FA, Wiezel GA, Cardoso IA, Ferreira IG, de Oliveira IS, Boldrini-França J, Pucca MB, Baldo MA, Arantes EC.
Front Pharmacol. 2020 Jul 24;11:1132. doi: 10.3389/fphar.2020.01132. eCollection 2020.
PMID: 32848750 Free PMC article. Review.

