Hydroxychloroquine

Hydroxychloroquine

Chemical compound and drug used in the form of hydroxychloroquine sulfate, used to to treat malaria, lupus and rheumatoid arthritis

Hydroxychloroquine sulfate is sold under the drug names Plaquenil and Ercoquin and used as a treatment or prophylaxis of malaria. Hydroxychloroquine is also used to treat lupus erythematosus and rheumatoid arthritis. Chloroquine is also given as a drug in the form of chloroquine phosphate under the drug name Aralen for the same indications. Overdose of chloroquine phosphate can cause acute poisoning and death. Hydroxychloroquine sulfate is a derivative of chloroquine phosphate that has been demonstrated to be 40% less toxic than chloroquine phosphate in animals, but prolonged and overdose usage can still cause poisoning.

Hydroxychloroquine sulfate is being tested in clinical trials for COVID-19 and has been shown to inhibit SARS-CoV-2 infection in vitro, in Vero E6 cells in culture.

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May 21, 2020
The Independent
A global trial is to begin in the UK of anti-malarial drug hydroxychloroquine which has been endorsed by Donald Trump as a Covid-19 preventative. On Thursday, British Health workers in Brighton and Oxford who are in regular contact with Covid-19 patients will be enrolled in the three month programme, which will either give them active versions of the drug, or a placebo.
Payal Banerjee
May 19, 2020
news.google.com
New Delhi, May 19 (PTI) Five hospitals have enrolled so far for an observational study being conducted by ICMR to assess the efficacy of anti-malarial drug hydroxychloroquine as a preventive medication against COVID-19 among healthcare personnel.
TIMESOFINDIA.COM
May 18, 2020
The Times of India
Hydroxychloroquine (HCQ) has become quite the buzz word in the times of COVID-19 and is being touted as one of the most promising drugs in the treatment of novel coronavirus.
Chris Ciaccia
May 12, 2020
Fox News
A large study of more than 1,400 COVID-19 patients has revealed the controversial coronavirus treatment hydroxychloroquine yielded no benefits for patients.
May 6, 2020
clinicaltrials.gov
Safety and Efficacy of Hydroxychloroquine + Favipiravir Drug Regimen in Comparison With Hydroxychloroquine + Kaletra on the Need for Intensive Care Unit Treatment in Patients With COVID-19 - Full Text View.
May 4, 2020
clinicaltrials.gov
Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19 - Full Text View.
April 30, 2020
clinicaltrials.gov
Treating COVID-19 With Hydroxychloroquine (TEACH) - Full Text View.
April 30, 2020
International Business Times UK
Hydroxychloroquine and Chloroquine are just one of the many drugs that have been promoted by doctors around the world.
April 27, 2020
clinicaltrials.gov
Protect: A Randomized Study With Hydroxychloroquine Versus Observational Support for Prevention and Early Phase Treatment of Coronavirus Disease (COVID-19) - Full Text View.
April 27, 2020
clinicaltrials.gov
Hydroxychloroquine as Prophylaxis for COVID-19 in Healthcare Workers (HCQPreP) - Full Text View.
April 27, 2020
clinicaltrials.gov
VA Remote and Equitable Access to COVID-19 Healthcare Delivery (VA-REACH TRIAL) - Full Text View.
April 24, 2020
clinicaltrials.gov
Chloroquine, Hydroxychloroquine or Only Supportive Care in Patients AdmItted With Moderate to Severe COVID-19 - Full Text View.
April 24, 2020
clinicaltrials.gov
Efficacy of Hydroxychloroquine, Telmisartan and Azithromycin on the Survival of Hospitalized Elderly Patients With COVID-19 - Full Text View.
April 24, 2020
clinicaltrials.gov
Effectiveness and Safety of Medical Treatment for SARS-CoV-2 (COVID-19) in Colombia - Full Text View.
By Ian Randall For Mailonline
April 23, 2020
Mail Online
Researchers from the University of Dundee will conduct trials of brensocatib - formerly known as INS1007 - to tackle lung inflammation caused by the virus.
Julia Carrie Wong in San Francisco
April 23, 2020
the Guardian
The head of a US government agency for investing in pandemic responses said he was forced out after resisting 'misguided directives' over hydroxychloroquine. Photograph: John Phillips/Getty Images
James Rogers
April 21, 2020
Fox News
Malaria drug hydroxychloroquine showed no benefit in a large study of its use in U.S. veterans hospitals, researchers say.
April 15, 2020
clinicaltrials.gov
An Open Randomized Study of the Effectiveness of Mefloquine for the Treatment of Patients With COVID19 - Full Text View.
April 15, 2020
clinicaltrials.gov
An Open Randomized Study of Dalargin Effectiveness in Patients With Severe and Critical Manifestations of SARS-COVID-19 - Full Text View.
April 3, 2020
clinicaltrials.gov
Convalescent Plasma for Patients With COVID-19: A Randomized, Open Label, Parallel, Controlled Clinical Study - Full Text View.
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