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The Compendium of Materia Medica or Bencao Gangmu, also the Great Pharmacopoeia,[1] is an encyclopedic gathering of medicine, natural history, and Chinese herbology compiled and edited by Li Shizhen and published in the late 16th century, during the Ming dynasty. Its first draft was completed in 1578 and printed in Nanjing in 1596. The Compendium lists the materia medica of traditional Chinese medicine known at the time, including plants, animals, and minerals that were believed to have medicinal properties. Over the centuries it was reprinted, translated, and cited widely. In the twentieth century was adopted as a basis for Traditional Chinese Medicine.