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US Patent 9957315 Purification of cell culture derived alpha1 protease inhibitor

Patent 9957315 was granted and assigned to Grifols on May, 2018 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Grifols
Grifols
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Current Assignee
Grifols
Grifols
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
99573150
Patent Inventor Names
Jennifer A. Hunt0
Tonny Dessources0
Thomas P. Zimmerman0
Charles Miller0
David Ownby0
Senthil Ranganathan0
Date of Patent
May 1, 2018
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Patent Application Number
151386820
Date Filed
April 26, 2016
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Patent Primary Examiner
‌
Gary B. Nickol
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Patent abstract

Described herein are methods for purifying recombinant, cell culture derived alpha1-protease inhibitor and removing a colored species that co-purifies with the recA1PI protein. Also described are methods for reducing the iron in cell culture derived alpha1-protease inhibitor.

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