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US Patent 9856214 EBNA1 inhibitors and their method of use

Patent 9856214 was granted and assigned to The Wistar Institute on January, 2018 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
The Wistar Institute
The Wistar Institute
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Current Assignee
The Wistar Institute
The Wistar Institute
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
98562140
Patent Inventor Names
Troy E. Messick0
Paul M. Lieberman0
Yan Zhang0
Venkata Velvadapu0
Allen B. Reitz0
Garry R. Smith0
Mark E. McDonnell0
Date of Patent
January 2, 2018
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Patent Application Number
150362110
Date Filed
November 14, 2014
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Patent Primary Examiner
‌
Shengjun Wang
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Patent abstract

The invention provides EBNA1 inhibitors, and pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by EBNA1 activity such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The compounds and compositions of the invention are further useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. The compounds and compositions of the invention are further useful for the treatment of diseases caused by lytic EBV infection.

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