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US Patent 9732373 Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence

Patent 9732373 was granted and assigned to Promega (company) on August, 2017 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Promega
Promega
Current Assignee
Promega
Promega
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9732373
Date of Patent
August 15, 2017
Patent Application Number
14851608
Date Filed
September 11, 2015
Patent Citations Received
‌
US Patent 11788068 Modified/mutant bacterial luciferases
Patent Primary Examiner
‌
Karen Cochrane Carlson
Patent abstract

Provided herein are isolated polynucleotide encoding modified click beetle luciferase polypeptides that have enhanced luminescence and longer wavelength near-infrared signals. The disclosure also relates to near-infrared bioluminescence systems that include said modified click beetle luciferase polypeptides and novel luciferin derivatives, as well as methods of using said modified click beetle luciferase polypeptides and bioluminescence systems.

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