Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jeffrey N. Agar0
Joseph Salisbury0
Date of Patent
August 30, 2016
Patent Application Number
14440978
Date Filed
November 15, 2013
Patent Citations Received
Patent Primary Examiner
Patent abstract
Described herein are compounds and methods for tethering proteins. For example, dimers of proteins, including SOD1 and DJ-1, are described, where the dimers are formed by the covalent bonding of a cysteine on the first monomer to a cysteine on the second monomer via a cyclic disulfide linker. The covalently attached dimers exhibit increased stabilization.
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