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US Patent 8486455 Polymeric delivery formulations of leuprolide with improved efficacy

Patent 8486455 was granted and assigned to Tolmar on July, 2013 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
Tolmar
Tolmar
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8486455
Date of Patent
July 16, 2013
Patent Application Number
12784304
Date Filed
May 20, 2010
Patent Primary Examiner
‌
Michael G. Hartley
Patent abstract

The present invention is directed to a flowable composition that is suitable for use as a controlled release implant. The flowable composition includes a biodegradable thermoplastic polyester that is at least substantially insoluble in aqueous medium or body fluid. The flowable composition also includes a biocompatible polar aprotic solvent. The biocompatible polar aprotic solvent is miscible to dispersible in aqueous medium or body fluid. The flowable composition also includes leuprolide acetate.

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