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US Patent 8420595 Methods for treating acute acoustic trauma

Patent 8420595 was granted and assigned to Oklahoma Medical Research Foundation on April, 2013 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
Oklahoma Medical Research Foundation
Oklahoma Medical Research Foundation
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8420595
Patent Inventor Names
Richard Dana Kopke0
Robert A. Floyd0
Date of Patent
April 16, 2013
Patent Application Number
12374970
Date Filed
July 25, 2007
Patent Citations Received
‌
US Patent 11857551 Methods for the prevention and treatment of hearing loss
0
‌
US Patent 11766440 Methods for the prevention and treatment of hearing loss
Patent Primary Examiner
‌
Richard Schnizer
Patent abstract

The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition includes compounds which function as free radical traps such as phenyl butyl nitrone (PBN), free radical scavengers, such as edaravone, resveratrol, ebselen and iron chelator and compounds from the family of antioxidant compounds including, but not limited to, N-acetylcysteine (NAC), Acetyl-L-Carnitine (ALCAR), glutathione monoethylester, ebselen, D-methionine and carbamathione. The compositions of the current invention may be delivered by injections or orally.

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