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US Patent 8252811 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof

Patent 8252811 was granted and assigned to Memory Pharmaceuticals on August, 2012 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
‌
Memory Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8252811
Patent Inventor Names
Brian Herbert0
Wenge Xie0
Truc Nguyen0
Ashok Tehim0
Carla Gauss0
Date of Patent
August 28, 2012
Patent Application Number
13338835
Date Filed
December 28, 2011
Patent Primary Examiner
‌
Andrew D. Kosar
Patent abstract

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

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