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US Patent 8124619 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof

Patent 8124619 was granted and assigned to Targacept, Inc. on February, 2012 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to pharmaceutical compositions incorporating compounds capable of affecting nicotinic acetylcholinergic receptors (nAChRs), for example, as modulators of specific nicotinic receptor subtypes (specifically, the α7 nAChR subtype). The present invention also relates to methods for treating a wide variety of conditions and disorders, particularly those associated with dysfunction of the central and autonomic nervous systems.

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