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US Patent 7785857 Protein C variant

Patent 7785857 was granted and assigned to Saint Louis University Hospital on August, 2010 by the United States Patent and Trademark Office.

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Current Assignee
Saint Louis University Hospital
Saint Louis University Hospital
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7785857
Date of Patent
August 31, 2010
Patent Application Number
11848080
Date Filed
August 30, 2007
Patent Primary Examiner
‌
Sheridan Swope
Patent abstract

This invention relates to a novel form of protein C or activated protein C. More specifically, the invention is directed to a variant of protein C that is activated at a higher rate than wild-type or other variants and produces an activated protein C with reduced anticoagulant properties while retaining the protective anti-inflammatory and anti-apoptotic properties of wild-type activated protein C. This novel APC variant will be beneficial for treating inflammatory and apoptotic disorders with a reduced risk for bleeding.

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