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US Patent 7727969 Controlled release nanoparticle having bound oligonucleotide for targeted delivery

Patent 7727969 was granted and assigned to Massachusetts Institute of Technology on June, 2010 by the United States Patent and Trademark Office.

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Current Assignee
Massachusetts Institute of Technology
Massachusetts Institute of Technology
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7727969
Date of Patent
June 1, 2010
Patent Application Number
10456978
Date Filed
June 6, 2003
Patent Citations Received
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US Patent 11957788 Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
0
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US Patent 11779641 Tolerogenic synthetic nanocarriers for allergy therapy
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US Patent 11913012 Cardiac cell reprogramming with myocardin and ASCL1
0
Patent Primary Examiner
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David M. Naff
Patent abstract

The present invention relates to a conjugate that includes a nucleic acid ligand bound to a controlled release polymer system, a pharmaceutical composition that contains the conjugate, and methods of treatment using the conjugate. The controlled release polymer system includes an agent such as a therapeutic, diagnostic, prognostic, or prophylactic agent. The nucleic acid ligand that is bound to the controlled release polymer system, binds selectively to a target, such as a cell surface antigen, and thereby delivers the controlled release polymer system to the target.

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