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US Patent 7411043 Slo4 potassium channel proteins

Patent 7411043 was granted and assigned to Icagen, Inc. on August, 2008 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
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Icagen, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
74110430
Patent Inventor Names
Julie Dickson Witzel0
Timothy James Jegla0
Date of Patent
August 12, 2008
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Patent Application Number
113257640
Date Filed
January 4, 2006
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Patent Primary Examiner
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Michael Pak
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Patent abstract

The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4.

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