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US Patent 7399839 Monopegylated growth hormone proteins

Patent 7399839 was granted and assigned to Bolder Biotechnology on July, 2008 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
‌
Bolder Biotechnology
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7399839
Date of Patent
July 15, 2008
Patent Application Number
11093477
Date Filed
March 29, 2005
Patent Citations Received
‌
US Patent 11925689 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same
0
‌
US Patent 11857602 Growth hormone antagonist and anti-cancer composition combination therapy
0
Patent Primary Examiner
‌
Manjunath Rao
Patent abstract

The present invention relates to novel methods of making soluble proteins having free cysteines in which a host cell is exposed to a cysteine blocking agent. The soluble proteins produced by the methods can then be modified to increase their effectiveness. Such modifications include attaching a PEG moiety to form pegylated proteins.

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