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US Patent 7195871 Methods and compositions for detecting target sequences

Patent 7195871 was granted and assigned to Third Wave Technologies on March, 2007 by the United States Patent and Trademark Office.

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Current Assignee
Third Wave Technologies
Third Wave Technologies
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
71958710
Patent Inventor Names
Bruce P. Neri0
Victor Lyamichev0
Andrew A. Lukowiak0
Jeff Hall0
Date of Patent
March 27, 2007
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Patent Application Number
102903860
Date Filed
November 7, 2002
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Patent Citations Received
‌
US Patent 12060620 Multiplexed KRAS mutation detection assay
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Patent Primary Examiner
Young J. Kim
Young J. Kim
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Patent abstract

The present invention relates to compositions and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. For example, in some embodiments, a 5′ nuclease activity from any of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

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