Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Daniel J. Powell, Jr.0
Silvana Canevari0
Mariangela Figini0
Date of Patent
October 22, 2024
0Patent Application Number
170763590
Date Filed
October 21, 2020
0Patent Citations
...
Patent Primary Examiner
Patent abstract
The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having α-folate receptor (FRα) binding domain and CD27 costimulatory domain to treat ovarian cancer. In an embodiment, the FRα binding domain is fully human, thereby preventing a host immune response.
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