Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Byong Kang0
Henry C. Nguyen0
Renee L. Greer0
Yik Andy Yeung0
Ivana Djuretic0
David Liu0
Date of Patent
October 22, 2024
0Patent Application Number
183074770
Date Filed
April 26, 2023
0Patent Citations
...
Patent Primary Examiner
Patent abstract
The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.
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