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US Patent 12060611 Gene expression profiles associated with sub-clinical kidney transplant rejection

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Is a
Patent
Patent
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Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
120606110
Patent Inventor Names
Sunil Kurian0
Steve Head0
John Friedewald0
Daniel Salomon0
Phillip Ordoukhanian0
Michael M. Abecassis0
Date of Patent
August 13, 2024
0
Patent Application Number
165691190
Date Filed
September 12, 2019
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Patent Citations
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US Patent RE39920 Methods for detection of nucleic acid sequences in urine
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US Patent 7415358 Molecular toxicology modeling
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US Patent 7426441 Methods for determining renal toxins
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US Patent 7615355 Peripheral-type benzodiazepine receptor expression level as an index of organ damage and regeneration
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US Patent 7645575 Genes useful for diagnosing and monitoring inflammation related disorders
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US Patent 7741038 Methods and compositions for evaluating graft survival in a solid organ transplant recipient
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US Patent 7785797 Methods and compositions for diagnosing and monitoring transplant rejection
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US Patent 7811767 Methods and compositions for assessing acute rejection
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...
Patent Primary Examiner
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Jehanne S Sitton
0
Patent abstract

By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.

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