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US Patent 11998482 Method and apparatus for subretinal administration of therapeutic agent

Patent 11998482 was granted and assigned to Gyroscope Therapeutics on June, 2024 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
Gyroscope Therapeutics
Gyroscope Therapeutics
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Current Assignee
Gyroscope Therapeutics
Gyroscope Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119984820
Patent Inventor Names
Nathan D. Grubbs0
Leah R. Soffer0
Brendan J. Oberkircher0
Daniel J. Yasevac0
Isaac J. Khan0
Daniel W. Price0
Saeed Sokhanvar0
Michel G. Bruehwiler0
...
Date of Patent
June 4, 2024
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Patent Application Number
173466540
Date Filed
June 14, 2021
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Patent Citations
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US Patent 8425473 Subretinal access device
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US Patent 8808225 Methods and devices for drug delivery to ocular tissue using microneedle
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US Patent 9668917 Drug delivery treatment device
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US Patent 10226379 Method and apparatus for subretinal administration of therapeutic agent
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US Patent 11554042 Method and apparatus for subretinal administration of therapeutic agent
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US Patent 11058576 Method and apparatus for subretinal administration of therapeutic agent
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US Patent 7189245 Subretinal implantation device and surgical cannulas for use therewith
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US Patent 7207980 Composite ophthalmic microcannula
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...
Patent Primary Examiner
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Theodore J Stigell
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CPC Code
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A61M 2210/0612
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A61M 2005/1585
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A61M 5/158
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A61F 9/0008
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A61F 9/0017
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Patent abstract

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

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