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US Patent 11993651 Anti-lag-3 antibodies and methods of use thereof

Patent 11993651 was granted and assigned to Agenus on May, 2024 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
0

Patent attributes

Patent Applicant
Agenus
Agenus
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Current Assignee
Agenus
Agenus
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119936510
Patent Inventor Names
David Adam Savitsky0
Cornelia Anne Mundt0
Marc van Dijk0
Nicholas Stuart Wilson0
Shawn Michael Jennings0
Date of Patent
May 28, 2024
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Patent Application Number
171000380
Date Filed
November 20, 2020
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Patent Citations
‌
US Patent 7411057 Nucleic acids encoding human monoclonal antibodies to CTLA-4
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US Patent 7488802 Antibodies against PD-1
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US Patent 7658921 Molecules with extended half-lives, compositions and uses thereof
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US Patent 7709226 Method of humanizing antibodies by matching canonical structure types CDRs
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US Patent 7858589 Compositions of CpG and saponin adjuvants and uses thereof
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US Patent 7943743 Human monoclonal antibodies to programmed death ligand 1 (PD-L1)
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US Patent 7951917 Method for making multispecific antibodies having heteromultimeric and common components
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US Patent 7972993 Identification of protein binding sites
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...
Patent Primary Examiner
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Michail A Belyavskyi
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Patent abstract

The instant disclosure provides antibodies that specifically bind to LAG-3 (e.g., human LAG-3) and antagonize LAG-3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

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