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US Patent 11939383 B7-H4 antibodies and methods and use thereof

Patent 11939383 was granted and assigned to Five Prime Therapeutics on March, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Five Prime Therapeutics
Five Prime Therapeutics
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Current Assignee
Five Prime Therapeutics
Five Prime Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119393830
Patent Inventor Names
Hangil Park0
Majid Ghoddusi0
Nerissa Mendoza0
Kathy Miller0
Alessandro Palumbo0
Charles Kaplan0
Date of Patent
March 26, 2024
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Patent Application Number
170066700
Date Filed
August 28, 2020
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Patent Citations
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US Patent 7619068 Ovr110 antibody compositions and methods of use
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US Patent 7622565 Nucleic acids encoding B7-H4, a T cell immunoregulatory molecule
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US Patent 7658921 Molecules with extended half-lives, compositions and uses thereof
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US Patent 6891030 T-cell immunoregulatory molecule
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US Patent 6946292 Cells producing antibody compositions with increased antibody dependent cytotoxic activity
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US Patent 7214775 Method of modulating the activity of functional immune molecules
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US Patent 7304149 BTLA nucleic acids
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US Patent 7504256 Process for producing polypeptide
0
...
Patent Primary Examiner
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Aurora M Fontainhas
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Patent abstract

The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4. The anti-B7-H4 antibodies or antigen-binding fragments thereof are useful, for example in detecting B7-H4. Immunohistochemistry (IHC) can be used to detect B7-H4. The present disclosure also provides methods for treating cancer wherein increased B7-H4 has been detected, by administering a therapeutic anti-B7-H4 antibody or antigen-binding fragment thereof.

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