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US Patent 11851491 Compositions and methods for TCR reprogramming using fusion proteins

Patent 11851491 was granted and assigned to Tcr2 Therapeutics Inc. on December, 2023 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
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Tcr2 Therapeutics Inc.
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Current Assignee
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Tcr2 Therapeutics Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118514910
Patent Inventor Names
Robert Hofmeister0
Patrick Baeuerle0
Date of Patent
December 26, 2023
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Patent Application Number
164624920
Date Filed
November 22, 2017
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Patent Citations
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US Patent 7067318 Methods for transfecting T cells
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US Patent 7081518 Anti-mesothelin antibodies having high binding affinity
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US Patent 7144575 Methods for selectively stimulating proliferation of T cells
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US Patent 7172869 Methods for transfecting T cells
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US Patent 7175843 Methods for selectively stimulating proliferation of T cells
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US Patent 7232566 Methods for treating HIV infected subjects
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US Patent 7371849 Methods of constructing camel antibody libraries
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US Patent 7572631 Activation and expansion of T cells
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Patent Primary Examiner
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Maria G Leavitt
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Patent abstract

Provided herein are T-cell receptor (TCR) fusion proteins (TFPs) having specificity for one or more tumor cell associated antigens, T cells engineered to express one or more TFP, and methods of use thereof for the treatment of diseases, including cancer.

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