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US Patent 11789010 Methods of treatment with CD80 extracellular domain polypeptides

Patent 11789010 was granted and assigned to Five Prime Therapeutics on October, 2023 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Five Prime Therapeutics

Current Assignee

Five Prime Therapeutics

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Susannah D. Barbee

Barbara Sennino

Ursula Jeffry

Thomas Brennan

Date of Patent

October 17, 2023

Patent Application Number

16608911

Date Filed

April 27, 2018

Patent Citations

US Patent 7794718 Immunosuppressive polypeptides and nucleic acids

US Patent 7968680 Polynucleotides encoding members of the human B lymphocyte activation antigen B7 family and polypeptides encoded thereby

US Patent 8114845 Compositions of PD-1 antagonists and methods of use

US Patent 8268788 Combination cancer immunotherapy with co-stimulatory molecules

US Patent 8956619 Soluble CD80 as a therapeutic to reverse immune supression in cancer patients

US Patent 8969526 Antibody Fc variants

US Patent 9220728 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes

US Patent 9308236 Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions

...

Patent Primary Examiner

CPC Code

G01N 2333/70532

Patent abstract

This application relates to use of CD80 (B7-1) extracellular domain (ECD) polypeptides and CD80-ECD fusion molecules and their use in methods of increasing the number of central memory T cells or for treatment for cancer or for use in cancer vaccine compositions.

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