Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Janani Krishnamurthy
Feng Wang-Johanning
Hiroki Torikai
Ling Zhang
Laurence J N Cooper
Helen Huls
Lenka Hurton
Simon Olivares
Date of Patent
October 17, 2023
Patent Application Number
17223597
Date Filed
April 6, 2021
Patent Citations
...
Patent Primary Examiner
Patent abstract
The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T-cells are producing using electroporation in conjunction with a transposon-based integration system to produce a population of CAR-expressing cells that require minimal ex vivo expansion or that can be directly administered to patients for disease (e.g., cancer) treatment.
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