Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Drew M. Pardoll
Bert Vogelstein
Luis Diaz
Nickolas Papadopoulos
Suzanne L. Topalian
Dung Le
Kenneth W. Kinzler
Date of Patent
September 12, 2023
Patent Application Number
17952919
Date Filed
September 26, 2022
Patent Citations
...
Patent Primary Examiner
Blockade of immune checkpoints such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-1 (PD-1) shows promise in patients with cancer. Inhibitory antibodies directed at these receptors have been shown to break immune tolerance and promote anti-tumor immunity. These agents work particularly well in patients with a certain category of tumor. Such tumors may be particularly susceptible to treatment because of the multitude of neoantigens which they produce.
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