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US Patent 11654193 Cancer treatment combinations

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Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116541930
Date of Patent
May 23, 2023
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Patent Application Number
168708030
Date Filed
May 8, 2020
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Patent Citations
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US Patent 8992910 IL3Rα antibody conjugates and uses thereof
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US Patent 9228023 Anti-ROR1 antibodies and methods of use for treatment of cancer
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US Patent 9228208 Methods and compositions for the targeted modification of a genome
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US Patent 9260512 Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system
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US Patent 9758591 Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
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US Patent 10344096 Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
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US Patent 10688181 Cancer treatment combinations
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US Patent 7138501 Antibodies that immunospecifically bind BLyS
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...
Patent Primary Examiner
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Karen A. Canella
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CPC Code
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A61K 2039/505
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A61K 2300/00
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A61K 45/06
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There are provided, inter alia, compositions and methods for treatment of cancer. The methods include administering to a subject in need a therapeutically effective amount of a Bruton's tyrosine kinase (BTK) antagonist and a ROR-1 antagonist. Further provided are pharmaceutical compositions including a BTK antagonist, ROR-1 antagonist and a pharmaceutically acceptable excipient. In embodiments, the BTK antagonist is ibrutinib and the ROR-1 antagonist is cirmtuzumab.

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