US Patent 11459558 Methods for using transcription-dependent directed evolution of AAV capsids

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Patent

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Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

11459558

Date of Patent

October 4, 2022

Patent Application Number

17337341

Date Filed

June 2, 2021

Patent Citations

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US Patent 10155931 Scalable production method for AAV

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US Patent 10041090 Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby

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US Patent 10113182 Subfamily E simian adenoviruses A1302, A1320, A1331 and A1337 and uses thereof

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US Patent 10137176 Compositions and methods for treating MPSI

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US Patent 10138295 Compositions comprising AAV expressing dual antibody constructs and uses thereof

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US Patent 10149873 Subfamily E simian adenoviruses A1321, A1325, A1295, A1309, A1316 and A1322 and uses thereof

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US Patent 10570395 Modulatory polynucleotides

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US Patent 10577627 Chimeric capsids

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Patent Citations Received

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US Patent 11859200 AAV capsids with increased tropism to brain tissue

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US Patent 12084654 Methods for using transcription-dependent directed evolution of AAV capsids

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US Patent 12084653 Methods for using transcription-dependent directed evolution of AAV capsids

Patent Primary Examiner

CPC Code

Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods.

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US Patent 11459558 Methods for using transcription-dependent directed evolution of AAV capsids

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