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US Patent 11459392 Anti-CD70 antibody drug conjugates

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Patent
Patent

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Patent Applicant
Ambrx
Ambrx
Current Assignee
Ambrx
Ambrx
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11459392
Date of Patent
October 4, 2022
Patent Application Number
16224346
Date Filed
December 18, 2018
Patent Primary Examiner
‌
Christina Bradley

This invention relates to anti-CD70 antibodies and antibody drug conjugates comprising at least one non-naturally-encoded amino acid. Disclosed herein are αCD70 antibodies with one or more non-naturally encoded amino acids and further disclosed are antibody drug conjugates wherein the αCD70 antibodies of the invention are conjugated to one or more toxins. Further disclosed are methods for using such non-natural amino acid antibody drug conjugates, including therapeutic, diagnostic, and other biotechnology uses.

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