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US Patent 11441175 Methods and kits for depleting undesired nucleic acids

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Is a
Patent
Patent

Patent attributes

Patent Applicant
‌
Bioo Scientific
Current Assignee
‌
Bioo Scientific
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11441175
Date of Patent
September 13, 2022
Patent Application Number
15905952
Date Filed
February 27, 2018
Patent Primary Examiner
‌
Angela M Bertagna
CPC Code
‌
C12Q 1/6806
‌
C12Q 1/6888
‌
C12Q 1/6832
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C12Q 1/6855
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C12Q 1/686
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C12Q 1/6811
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C12Q 2600/16
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C12Q 1/6874
...

Methods and kits for depleting amplicons that correspond to undesired RNA species present in a sample are provided. The disclosed methods and kits employ a blocker that anneals with at least a portion of the undesired RNA, resulting in a duplex that is not a suitable substrate for ligating an adapter to the end of the undesired RNA.

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