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US Patent 11248236 Non-HLA matched humanized NSG mouse model with patient-derived xenograft

Patent 11248236 was granted and assigned to The Jackson Laboratory on February, 2022 by the United States Patent and Trademark Office.

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Patent Applicant
The Jackson Laboratory
The Jackson Laboratory
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Current Assignee
The Jackson Laboratory
The Jackson Laboratory
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
112482360
Patent Inventor Names
James Keck0
Date of Patent
February 15, 2022
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Patent Application Number
158500530
Date Filed
December 21, 2017
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Patent Primary Examiner
‌
Janet L Epps-Smith
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Patent abstract

The invention described herein provides non-HLA matched humanized mouse model (e.g., NSG mouse model) with patient-derived xenograft (PDX), as well as methods of making and using the same.

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