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US Patent 11225653 Methods and compounds for reducing threonyl-tRNA synthetase activity

Patent 11225653 was granted and assigned to University of Vermont on January, 2022 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
University of Vermont
University of Vermont
Current Assignee
University of Vermont
University of Vermont
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11225653
Patent Inventor Names
Karen M. Lounsbury0
Christopher Francklyn0
Jason Botten0
Date of Patent
January 18, 2022
Patent Application Number
16134481
Date Filed
September 18, 2018
Patent Primary Examiner
‌
Lei Yao
Patent abstract

The invention includes, in part, methods and compounds for treating diseases and conditions characterized by elevated threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to diseases and conditions in which angiogenesis is elevated as compared to normal. In some embodiments of the invention, a level of a TARS molecule is determined and compared to a control level of TARS to assess a treatment for a disease or condition characterized by elevated TARS activity.

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