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US Patent 11021762 DNA impurities in a composition comprising a parvoviral virion

Patent 11021762 was granted and assigned to uniQure on June, 2021 by the United States Patent and Trademark Office.

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Patent
Patent

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Patent Applicant
uniQure
uniQure
Current Assignee
uniQure
uniQure
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11021762
Date of Patent
June 1, 2021
Patent Application Number
15531095
Date Filed
November 27, 2015
Patent Primary Examiner
‌
Jennifer Dunston
Patent abstract

The current invention relates to nucleic acid impurities in a composition comprising a parvoviral vector. In particular, the current invention shows that DNA impurities are not randomly encapsulated within a parvoviral virion. The invention therefore relates to a method for identifying and quantifying a nucleic acid impurity in a composition comprising a parvoviral vector. Finally, the current invention relates to method of determining whether a composition comprising a parvoviral vector is regarded as clinically pure.

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