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US Patent 10544221 Single chain variable fragment CD3 binding proteins

Patent 10544221 was granted and assigned to Harpoon Therapeutics on January, 2020 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
Harpoon Therapeutics
Harpoon Therapeutics
Current Assignee
Harpoon Therapeutics
Harpoon Therapeutics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10544221
Date of Patent
January 28, 2020
Patent Application Number
15600264
Date Filed
May 19, 2017
Patent Citations
‌
US Patent 10066016 Single chain variable fragment CD3 binding proteins
Patent Citations Received
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US Patent 12084518 Trispecific binding proteins and methods of use
0
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US Patent 11623958 Single chain variable fragment CD3 binding proteins
0
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US Patent 11607453 Mesothelin binding proteins
0
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US Patent 11976125 B cell maturation antigen binding proteins
0
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US Patent 11555078 Compositions and methods related to tumor activated antibodies targeting PSMA and effector cell antigens
Patent Primary Examiner
‌
Zachary S Skelding
Patent abstract

Disclosed herein are single chain variable fragment CD3 binding proteins with improved binding affinities, and robust aggregation profiles. Also described are multispecific binding proteins comprising a single chain variable fragment CD3 binding protein according to the instant disclosure. Pharmaceutical compositions comprising the binding proteins disclosed herein and methods of using such formulations are provided.

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