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US Patent 10532019 Botulinum nanoemulsions

Patent 10532019 was granted and assigned to University of Massachusetts Lowell on January, 2020 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
University of Massachusetts Lowell
University of Massachusetts Lowell
Current Assignee
University of Massachusetts Lowell
University of Massachusetts Lowell
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10532019
Date of Patent
January 14, 2020
Patent Application Number
15643945
Date Filed
July 7, 2017
Patent Citations
‌
US Patent 10016364 Compositions and methods for making and using nanoemulsions
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US Patent 10016451 Nucleic acid nanoparticles and uses therefor
Patent Citations Received
‌
US Patent 11311496 Transdermal delivery of large agents
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US Patent 10744078 Compositions and methods for topical application and transdermal delivery of botulinum toxins
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US Patent 10973890 Non-protein clostridial toxin compositions
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US Patent 11259740 Methods useful in optimizing the treatment of neuropathies and targeting tissues with cosmetic botulinum injections
Patent Primary Examiner
‌
Nita M. Minnifield
Patent abstract

The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.

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