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US Patent 10350432 Method and apparatus for preventing neurodegeneration

Patent 10350432 was granted and assigned to The Jackson Laboratory on July, 2019 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
The Jackson Laboratory
The Jackson Laboratory
Current Assignee
The Jackson Laboratory
The Jackson Laboratory
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10350432
Patent Inventor Names
Simon W. M. John0
Michael Anderson0
Richard Libby0
Date of Patent
July 16, 2019
Patent Application Number
15668764
Date Filed
August 4, 2017
Patent Primary Examiner
‌
Chang-Yu Wang
Patent abstract

A method for treating, preventing and/or reducing neurodegeneration in subjects with neurodegenerative disease, such as those neurodegenerative diseases that affect the eye, including glaucoma, using radiation, such as gamma radiation or X-ray radiation, either alone or together with a bone marrow transfer treatment. The method includes irradiating a targeted area of an animal, such as the eye region, with radiation, either alone or followed by injection with T-cell depleted bone marrow cells. Also a method for screening and/or selecting agents and/or treatment methods for inhibiting, treating and/or reducing neurodegeneration, particularly the neurodegeneration of the eye that occurs as a consequence of glaucoma.

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