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US Patent 10214747 Method of purifying monoclonal antibodies

Patent 10214747 was granted and assigned to Kentucky BioProcessing on February, 2019 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Kentucky BioProcessing
Kentucky BioProcessing
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Current Assignee
Kentucky BioProcessing
Kentucky BioProcessing
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
102147470
Patent Inventor Names
Steven D. Hume0
Josh Morton0
Kelsi Swope0
Larry Zeitlin0
Barry Bratcher0
Emmett Ernest Hiatt, III0
Date of Patent
February 26, 2019
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Patent Application Number
151102000
Date Filed
October 3, 2014
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Patent Primary Examiner
‌
Daniel E Kolker
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Patent abstract

A new platform method to purify plant-based monoclonal antibodies is provided. Such a method includes an antibody purification platform that involves a standardized procedure for the production of a wide array of different antibodies within a simplified context. The versatility of the overall purification process accords a one-size-fits-all approach for myriad antibody products and includes plant tissue harvesting, extraction and clarification, filtrate generation, a succession of column chromatography procedures, and buffer exposure to provide the desired monoclonal antibodies in proper filtered and purified form for further incorporation and/or use within medicaments and other formulations. Thus, the purified monoclonal antibodies produced thereby such a method are also encompassed within this invention.

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