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US Patent 10023608 Protein purification methods to remove impurities

Patent 10023608 was granted and assigned to Amgen on July, 2018 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Amgen
Amgen
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Current Assignee
Amgen
Amgen
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
100236080
Patent Inventor Names
Junfen Ma0
Xiaoyang Zhao0
Brian Williamson0
Date of Patent
July 17, 2018
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Patent Application Number
142080430
Date Filed
March 13, 2014
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Patent Citations Received
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US Patent 12070502 Process for reducing subvisible particles in a pharmaceutical formulation
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US Patent 11680930 Methods and systems for chromatography data analysis
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US Patent 11333642 Methods and systems for chromatography data analysis
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US Patent 11369896 Methods for quantitating individual antibodies from a mixture
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US Patent 11850535 Methods for quantitating individual antibodies from a mixture
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US Patent 11884698 Systems and methods for preparing a polypeptide from a mixture
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0
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US Patent 11571636 Methods for quantitating individual antibodies from a mixture
Patent Primary Examiner
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Daniel E Kolker
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Patent abstract

Disclosed are methods of purifying a protein sample. More specifically, provide are methods of removing or reducing the amount of high molecular weight species and/or high mannose species from a protein sample using a mixed mode chromatography step and a hydrophobic interaction chromatography step.

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