Medici family, French Médicis, Italian bourgeois family that ruled Florence and, later, Tuscany during most of the period from 1434 to 1737, except for two brief intervals (from 1494 to 1512 and from 1527 to 1530). It provided the Roman Catholic Church with four popes (Leo X, Clement VII, Pius IV, and Leon XI) and married into the royal families of Europe (most notably in France, in the persons of Queens Catherine de Médici and Marie de Médicis).
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