List of patents in the RNA-based and RNA-targeted therapeutics industry

Patents where

Current Assignee

Industry

Name	Description	Patent Applicant	Current Assignee	Patent Jurisdiction	Patent Number	Date of Patent
‌ US Patent 10369216 Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant	Patent 10369216 was granted and assigned to CureVac on August, 2019 by the United States Patent and Trademark Office.	CureVac	CureVac	United States Patent and Trademark Office	10369216	August 6, 2019
‌ US Patent 11110166 Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant	Patent 11110166 was granted and assigned to CureVac on September, 2021 by the United States Patent and Trademark Office.	CureVac	CureVac	United States Patent and Trademark Office	11110166	September 7, 2021
‌ US Patent 8431693 Process for desilylation of oligonucleotides	Patent 8431693 was granted and assigned to Alnylam Pharmaceuticals on April, 2013 by the United States Patent and Trademark Office.		Alnylam Pharmaceuticals	United States Patent and Trademark Office	8431693	April 30, 2013
‌ US Patent 11136585 UTRs increasing the translation efficiency of RNA molecules	Patent 11136585 was granted and assigned to ethris GmbH on October, 2021 by the United States Patent and Trademark Office.	Ethris	Ethris	United States Patent and Trademark Office	11136585	October 5, 2021
‌ US Patent 8968746 Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation	Patent 8968746 was granted and assigned to CureVac on March, 2015 by the United States Patent and Trademark Office.		CureVac	United States Patent and Trademark Office	8968746	March 3, 2015
‌ US Patent 8013136 Oligonucleotides comprising a non-phosphate backbone linkage	Patent 8013136 was granted and assigned to Alnylam Pharmaceuticals on September, 2011 by the United States Patent and Trademark Office.		Alnylam Pharmaceuticals	United States Patent and Trademark Office	8013136	September 6, 2011
‌ US Patent 7723512 Oligonucleotides comprising a non-phosphate backbone linkage	Patent 7723512 was granted and assigned to Alnylam Pharmaceuticals on May, 2010 by the United States Patent and Trademark Office.		Alnylam Pharmaceuticals	United States Patent and Trademark Office	7723512	May 25, 2010
‌ US Patent 7615618 Oligonucleotides comprising a non-phosphate backbone linkage	Patent 7615618 was granted and assigned to Alnylam Pharmaceuticals on November, 2009 by the United States Patent and Trademark Office.		Alnylam Pharmaceuticals	United States Patent and Trademark Office	7615618	November 10, 2009
‌ US Patent 7632932 Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase	Patent 7632932 was granted and assigned to Alnylam Pharmaceuticals on December, 2009 by the United States Patent and Trademark Office.		Alnylam Pharmaceuticals	United States Patent and Trademark Office	7632932	December 15, 2009
‌ US Patent 11780823 Indazole-3-carboxamides and their use as Wnt/β-catenin signaling pathway inhibitors	Patent 11780823 was granted and assigned to Biosplice Therapeutics on October, 2023 by the United States Patent and Trademark Office.	Biosplice Therapeutics	Biosplice Therapeutics	United States Patent and Trademark Office	11780823	October 10, 2023
‌ US Patent 11697649 Indazole inhibitors of the Wnt signal pathway and therapeutic uses thereof	Patent 11697649 was granted and assigned to Biosplice Therapeutics on July, 2023 by the United States Patent and Trademark Office.	Biosplice Therapeutics	Biosplice Therapeutics	United States Patent and Trademark Office	11697649	July 11, 2023
‌ US Patent 8999351 Lipids and compositions for the delivery of therapeutics	Patent 8999351 was granted and assigned to Tekmira Pharmaceuticals Corporation on April, 2015 by the United States Patent and Trademark Office.		‌ Tekmira Pharmaceuticals Corporation	United States Patent and Trademark Office	8999351	April 7, 2015
‌ US Patent 7893224 Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase	Patent 7893224 was granted and assigned to Alnylam Pharmaceuticals on February, 2011 by the United States Patent and Trademark Office.		Alnylam Pharmaceuticals	United States Patent and Trademark Office	7893224	February 22, 2011
‌ US Patent 11839688 Apparatus and method for cryogranulating a pharmaceutical composition	Patent 11839688 was granted and assigned to MannKind Corporation on December, 2023 by the United States Patent and Trademark Office.	MannKind	MannKind	United States Patent and Trademark Office	11839688	December 12, 2023
‌ US Patent 11241493 Coronavirus vaccine	Patent 11241493 was granted and assigned to CureVac on February, 2022 by the United States Patent and Trademark Office.	CureVac	CureVac	United States Patent and Trademark Office	11241493	February 8, 2022
‌ US Patent 9447431 Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein	Patent 9447431 was granted and assigned to CureVac on September, 2016 by the United States Patent and Trademark Office.		CureVac	United States Patent and Trademark Office	9447431	September 20, 2016
‌ US Patent 10111968 Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein	Patent 10111968 was granted and assigned to CureVac on October, 2018 by the United States Patent and Trademark Office.	CureVac	CureVac	United States Patent and Trademark Office	10111968	October 30, 2018
‌ US Patent 9669089 Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen	Patent 9669089 was granted and assigned to CureVac on June, 2017 by the United States Patent and Trademark Office.		CureVac	United States Patent and Trademark Office	9669089	June 6, 2017
‌ US Patent 10188748 Pharmaceutical composition containing a stabilised mRNA optimised for translation in its coding regions	Patent 10188748 was granted and assigned to CureVac on January, 2019 by the United States Patent and Trademark Office.		CureVac	United States Patent and Trademark Office	10188748	January 29, 2019
‌ US Patent 8951726 Multiplex detection of nucleic acids	Patent 8951726 was granted and assigned to Advanced Cell Diagnostics on February, 2015 by the United States Patent and Trademark Office.		Advanced Cell Diagnostics	United States Patent and Trademark Office	8951726	February 10, 2015
‌ US Patent 9572874 Composition comprising a complexed (M)RNA and a naked mRNA for providing or enhancing an immunostimulatory response in a mammal and uses thereof	Patent 9572874 was granted and assigned to CureVac on February, 2017 by the United States Patent and Trademark Office.		CureVac	United States Patent and Trademark Office	9572874	February 21, 2017
‌ US Patent 11471525 Coronavirus vaccine	Patent 11471525 was granted and assigned to CureVac on October, 2022 by the United States Patent and Trademark Office.	CureVac	CureVac	United States Patent and Trademark Office	11471525	October 18, 2022
‌ US Patent 11684615 Methods of using indazole-3-carboxamides and their use as Wnt/β-catenin signaling pathway inhibitors	Patent 11684615 was granted and assigned to Biosplice Therapeutics on June, 2023 by the United States Patent and Trademark Office.	Biosplice Therapeutics	Biosplice Therapeutics	United States Patent and Trademark Office	11684615	June 27, 2023
‌ US Patent 11149278 Artificial nucleic acid molecules for improved protein expression	Patent 11149278 was granted and assigned to CureVac on October, 2021 by the United States Patent and Trademark Office.	CureVac	CureVac	United States Patent and Trademark Office	11149278	October 19, 2021
‌ US Patent 9402887 Composition for treating prostate cancer (PCa)	Patent 9402887 was granted and assigned to CureVac on August, 2016 by the United States Patent and Trademark Office.	CureVac	CureVac	United States Patent and Trademark Office	9402887	August 2, 2016

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