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US Patent 9937257 Sulfated alginate hydrogels for cell culture and therapy

Patent 9937257 was granted and assigned to ETH Zurich on April, 2018 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
ETH Zurich
ETH Zurich
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Current Assignee
ETH Zurich
ETH Zurich
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
99372570
Patent Inventor Names
Marcy Zenobi-Wong0
Stefanie Moller0
Rami Mhanna0
Gemma Palazzolo0
Jana Becher0
Matthias Schnabelrauch0
Date of Patent
April 10, 2018
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Patent Application Number
144411770
Date Filed
November 4, 2013
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Patent Primary Examiner
‌
Taeyoon Kim
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Patent abstract

The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel.

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