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US Patent 9605084 Heterodimeric proteins

Patent 9605084 was granted and assigned to Xencor on March, 2017 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
Xencor
Xencor
Current Assignee
Xencor
Xencor
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9605084
Patent Inventor Names
John Desjarlais0
Gregory Moore0
Rumana Rashid0
Date of Patent
March 28, 2017
Patent Application Number
14200821
Date Filed
March 7, 2014
Patent Citations Received
‌
US Patent 11866507 Multispecific polypeptide constructs having constrained CD3 binding and methods of using the same
0
‌
US Patent 11945869 PD-1 single domain antibodies and therapeutic compositions thereof
0
‌
US Patent 11673945 Bispecific antigen binding proteins
0
Patent Primary Examiner
‌
Daniel C Gamett
Patent abstract

The present invention describes novel immunoglobulin compositions that co-engage at least two antigens, e.g. a first and second antigen, or, as outlined herein, three or four antigens can be bound, in some of the scaffold formats described herein. First and second antigens of the invention are herein referred to as antigen-1 and antigen-2 respectively (or antigen-3 and antigen-4, if applicable. As outlined herein, a number of different formats can be used, with some scaffolds relying combinations of monovalent and bivalent bindings.

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