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US Patent 9328159 Multimeric IL-15 soluble fusion molecules and methods of using same

Patent 9328159 was granted and assigned to Altor BioScience on May, 2016 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Altor BioScience
Altor BioScience
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Current Assignee
Altor BioScience
Altor BioScience
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
93281590
Patent Inventor Names
Peter Rhode0
Xiaoyun Zhu0
Bai Liu0
Hing C. Wong0
Kai-ping Han0
Date of Patent
May 3, 2016
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Patent Application Number
138549030
Date Filed
April 1, 2013
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Patent Citations Received
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US Patent 12016911 Bacillus Calmette-Guerin (BCG) and antigen presenting cells for treatment of bladder cancer
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US Patent 11857612 Bacillus Calmette-Guerin (BCG) and antigen presenting cells for treatment of bladder cancer
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US Patent 11872272 IL-15-based fusions to IL-12 and IL-18
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US Patent 11873338 CLEC12AxCD3 bispecific antibodies and methods for the treatment of disease
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US Patent 11890323 Method of treating cancer with composition comprising IL-15-based molecules and BCG
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US Patent 11919934 IL-15 conjugates and uses thereof
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US Patent 11925676 Method for treating neoplasia with an anti-CD38 antibody and an IL-15:IL-15R complex
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US Patent 11975059 IL-15-based fusions to IL-12 and IL-18
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...
Patent Primary Examiner
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Prema Mertz
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Patent abstract

The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).

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