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US Patent 8680237 Immunoglobulin constant region FC receptor binding agents

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Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8680237
Date of Patent
March 25, 2014
Patent Application Number
12602609
Date Filed
May 30, 2008
Patent Citations Received
‌
US Patent 12122836 Fusion proteins of human protein fragments to create orderly multimerized immunoglobulin Fc compositions with enhanced complement binding
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US Patent 12071482 Compositions and methods related to engineered Fc constructs
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US Patent 12084482 Fusion proteins of natural human protein fragments to create orderly multimerized immunoglobulin Fc compositions
0
Patent Primary Examiner
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Chun Dahle
Patent abstract

IVIG replacement compounds are derived from recombinant and/or biochemical creation of immunologically active biomimetic(s). These replacement compounds are then screened in vitro to assess each replacements compound's efficiency at modulating immune function. Particular replacement compounds are selected for further in vivo validation and dosage/administration optimization. Finally, the replacement compounds are used to treat a wide range of diseases, including inflammatory and autoimmune diseases.

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