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US Patent 7399460 Metal complexes derivatized with folate for use in diagnostic and therapeutic applications

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Ruth E. Wager0

Thangavel Arunachalam0

Kondareddiar Ramalingam0

Adrian D. Nunn0

Karen E. Linder0

Michael F. Tweedle0

Nataranjan Raju0

Paul W. Wedeking0

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Date of Patent

July 15, 2008

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Patent Application Number

115349190

Date Filed

September 25, 2006

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Patent Citations Received

US Patent 11931430 Labeled inhibitors of prostate specific membrane antigen (PSMA) as agents for the treatment of prostate cancer

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US Patent 11951190 Use of labeled inhibitors of prostate specific membrane antigen (PSMA), as agents for the treatment of prostate cancer

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US Patent 12091693 PSMA binding ligand-linker conjugates and methods for using

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Patent Primary Examiner

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Patent abstract

Diagnostic and therapeutic compositions in the form of complexes for enhancing transmembrane transport of a diagnostic or therapeutic agent and methods for their use. The complexes contain the α, γ, or bis isomers of folate receptor-binding analogs of folate, a metal chelated by a ligand, and in one embodiment, a chemotherapeutic agent.

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