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US Patent 12060435 Multi-specific ligand binders

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Patent
Patent
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Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120604350
Patent Inventor Names
John C. Williams0
Jeremy King0
Date of Patent
August 13, 2024
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Patent Application Number
169599810
Date Filed
January 7, 2019
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Patent Citations
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US Patent 11285207 Bispecific antibodies specifically binding to PD1 and LAG3
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US Patent 8987417 Covalently dimerized bivalent binding agents
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US Patent 9951145 CH3 domain variant pair inducing formation of heterodimer of heavy chain constant region of antibody at high efficiency, method for preparing same, and use thereof
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Patent Primary Examiner
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Claire Kaufman
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Patent abstract

Provided herein are, inter alia, novel peptide compositions having multi-specific binding capabilities useful for therapeutic and diagnostic purposes. The peptide compositions provided herein are polypeptide conjugates including at least two ligand binding domains able to target (bind) two or more ligands (e.g., antigens) at the same time. The peptide compositions provided herein can be produced at very high yields and are therefore easy to manufacture.

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